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Search Results for " agammaglobulinemia tyrosine kinase "
Targets Recommended: Src BTK

2

抑制剂 & 化合物

1

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T2603 Spebrutinib

CC-292,LMK-435,AVL-292

Src; BTK Angiogenesis; Tyrosine Kinase/Adaptors
Spebrutinib (LMK-435) 是一种共价的、高效的、选择性的、具有口服活性的Btk 抑制剂 (IC50:0.5 nM)。
T14357 Spebrutinib besylate

CC-292 (besylate),AVL-292 (benzenesulfonate)

BTK Angiogenesis; Tyrosine Kinase/Adaptors
Spebrutinib besylate (AVL-292 benzenesulfonate; CC-292 besylate) is a Btk kinase activity inhibitor (IC50<0.5 nM, Kinact/Ki=7.69×104 M-1s-1s).

化合物

Spebrutinib
Cat.No: T2603
Synonym: CC-292,LMK-435,AVL-292
Target: Src, BTK
Spebrutinib besylate
Cat.No: T14357
Synonym: CC-292 (besylate),AVL-292 (benzenesulfonate)
Target: BTK
Cat. No. Product Name Species Expression System
TMPH-02271 BTK Protein, Human, Recombinant (His)

BPK,AGMX1,ATK,B-cell progenitor kinase,Tyrosine...

Human Baculovirus Insect Cells
Non-receptor tyrosine kinase indispensable for B lymphocyte development, differentiation and signaling. Binding of antigen to the B-cell antigen receptor (BCR) triggers signaling that ultimately leads to B-cell activation. After BCR engagement and activation at the plasma membrane, phosphorylates PLCG2 at several sites, igniting the downstream signaling pathway through calcium mobilization, followed by activation of the protein kinase C (PKC) family members. PLCG2 phosphorylation is performed in...

重组蛋白

BTK Protein, Human, Recombinant (His)
Cat.No: TMPH-02271
Species: Human
Expression System: Baculovirus Insect Cells
TargetMol Loading
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